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Ribonucleotide reductase subunit switching in hepatoblastoma drug response and relapse

Prognosis of children with high-risk hepatoblastoma (HB), the most common pediatric liver cancer, remains poor. In this study, we found ribonucleotide reductase (RNR) subunit M2 (RRM2) was one of the key genes supporting cell proliferation in high-risk HB. While standard chemotherapies could effecti...

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Detalles Bibliográficos
Autores principales:	Brown, Anthony, Pan, Qingfei, Fan, Li, Indersie, Emilie, Tian, Cheng, Timchenko, Nikolai, Li, Liyuan, Hansen, Baranda S., Tan, Haiyan, Lu, Meifen, Peng, Junmin, Pruett-Miller, Shondra M., Yu, Jiyang, Cairo, Stefano, Zhu, Liqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992519/ https://www.ncbi.nlm.nih.gov/pubmed/36882565 http://dx.doi.org/10.1038/s42003-023-04630-7

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