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Inhibition of EPAC1 signaling pathway alters atrial electrophysiology and prevents atrial fibrillation
Introduction: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is associated with increased mortality and morbidity. The Exchange Protein directly Activated by cAMP (EPAC), has been implicated in pro-arrhythmic signaling pathways in the atria, but the underlying mechanism...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992743/ https://www.ncbi.nlm.nih.gov/pubmed/36909224 http://dx.doi.org/10.3389/fphys.2023.1120336 |