Inhibition of EPAC1 signaling pathway alters atrial electrophysiology and prevents atrial fibrillation

Introduction: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is associated with increased mortality and morbidity. The Exchange Protein directly Activated by cAMP (EPAC), has been implicated in pro-arrhythmic signaling pathways in the atria, but the underlying mechanism...

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Detalles Bibliográficos
Autores principales: Guillot, Bastien, Boileve, Arthur, Walton, Richard, Harfoush, Alexandre, Conte, Caroline, Sainte-Marie, Yannis, Charron, Sabine, Bernus, Olivier, Recalde, Alice, Sallé, Laurent, Brette, Fabien, Lezoualc’h, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992743/
https://www.ncbi.nlm.nih.gov/pubmed/36909224
http://dx.doi.org/10.3389/fphys.2023.1120336

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