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Histamine H(2) receptor deficit in glutamatergic neurons contributes to the pathogenesis of schizophrenia

Schizophrenia is a serious mental disorder, and existing antipsychotic drugs show limited efficacy and cause unwanted side effects. The development of glutamatergic drugs for schizophrenia is currently challenging. Most functions of histamine in the brain are mediated by the histamine H(1) receptor;...

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Detalles Bibliográficos
Autores principales: Ma, Qianyi, Jiang, Lei, Chen, Han, An, Dadao, Ping, Yiting, Wang, Yujia, Dai, Haibin, Zhang, Xiangnan, Wang, Yi, Chen, Zhong, Hu, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992765/
https://www.ncbi.nlm.nih.gov/pubmed/36812204
http://dx.doi.org/10.1073/pnas.2207003120