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Two differentially stable rDNA loci coexist on the same chromosome and form a single nucleolus

The nucleolus is the most prominent membraneless compartment within the nucleus—dedicated to the metabolism of ribosomal RNA. Nucleoli are composed of hundreds of ribosomal DNA (rDNA) repeated genes that form large chromosomal clusters, whose high recombination rates can cause nucleolar dysfunction...

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Detalles Bibliográficos
Autores principales: Lazar-Stefanita, Luciana, Luo, Jingchuan, Haase, Max A. B., Zhang, Weimin, Boeke, Jef D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992848/
https://www.ncbi.nlm.nih.gov/pubmed/36821584
http://dx.doi.org/10.1073/pnas.2219126120

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