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Two differentially stable rDNA loci coexist on the same chromosome and form a single nucleolus
The nucleolus is the most prominent membraneless compartment within the nucleus—dedicated to the metabolism of ribosomal RNA. Nucleoli are composed of hundreds of ribosomal DNA (rDNA) repeated genes that form large chromosomal clusters, whose high recombination rates can cause nucleolar dysfunction...
Autores principales: | Lazar-Stefanita, Luciana, Luo, Jingchuan, Haase, Max A. B., Zhang, Weimin, Boeke, Jef D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992848/ https://www.ncbi.nlm.nih.gov/pubmed/36821584 http://dx.doi.org/10.1073/pnas.2219126120 |
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