The role of Zn ions in the interaction between SARS-CoV-2 orf7a protein and BST2/tetherin

In this paper, we provide evidence that Zn[Formula: see text] ions play a role in the SARS-CoV-2 virus strategy to escape the immune response mediated by the BST2-tetherin host protein. This conclusion is based on sequence analysis and molecular dynamics simulations as well as X-ray absorption exper...

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Autores principales: Botticelli, S., Chiaraluce, R., Consalvi, V., La Penna, G., Pasquo, A., Petrosino, M., Proux, O., Rossi, G. C., Stellato, F., Morante, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992918/
https://www.ncbi.nlm.nih.gov/pubmed/36911363
http://dx.doi.org/10.1140/epjp/s13360-023-03731-w
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author Botticelli, S.
Chiaraluce, R.
Consalvi, V.
La Penna, G.
Pasquo, A.
Petrosino, M.
Proux, O.
Rossi, G. C.
Stellato, F.
Morante, S.
author_facet Botticelli, S.
Chiaraluce, R.
Consalvi, V.
La Penna, G.
Pasquo, A.
Petrosino, M.
Proux, O.
Rossi, G. C.
Stellato, F.
Morante, S.
author_sort Botticelli, S.
collection PubMed
description In this paper, we provide evidence that Zn[Formula: see text] ions play a role in the SARS-CoV-2 virus strategy to escape the immune response mediated by the BST2-tetherin host protein. This conclusion is based on sequence analysis and molecular dynamics simulations as well as X-ray absorption experiments [1].
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spelling pubmed-99929182023-03-08 The role of Zn ions in the interaction between SARS-CoV-2 orf7a protein and BST2/tetherin Botticelli, S. Chiaraluce, R. Consalvi, V. La Penna, G. Pasquo, A. Petrosino, M. Proux, O. Rossi, G. C. Stellato, F. Morante, S. Eur Phys J Plus Regular Article In this paper, we provide evidence that Zn[Formula: see text] ions play a role in the SARS-CoV-2 virus strategy to escape the immune response mediated by the BST2-tetherin host protein. This conclusion is based on sequence analysis and molecular dynamics simulations as well as X-ray absorption experiments [1]. Springer Berlin Heidelberg 2023-03-08 2023 /pmc/articles/PMC9992918/ /pubmed/36911363 http://dx.doi.org/10.1140/epjp/s13360-023-03731-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Regular Article
Botticelli, S.
Chiaraluce, R.
Consalvi, V.
La Penna, G.
Pasquo, A.
Petrosino, M.
Proux, O.
Rossi, G. C.
Stellato, F.
Morante, S.
The role of Zn ions in the interaction between SARS-CoV-2 orf7a protein and BST2/tetherin
title The role of Zn ions in the interaction between SARS-CoV-2 orf7a protein and BST2/tetherin
title_full The role of Zn ions in the interaction between SARS-CoV-2 orf7a protein and BST2/tetherin
title_fullStr The role of Zn ions in the interaction between SARS-CoV-2 orf7a protein and BST2/tetherin
title_full_unstemmed The role of Zn ions in the interaction between SARS-CoV-2 orf7a protein and BST2/tetherin
title_short The role of Zn ions in the interaction between SARS-CoV-2 orf7a protein and BST2/tetherin
title_sort role of zn ions in the interaction between sars-cov-2 orf7a protein and bst2/tetherin
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992918/
https://www.ncbi.nlm.nih.gov/pubmed/36911363
http://dx.doi.org/10.1140/epjp/s13360-023-03731-w
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