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Polo-like kinase 1 promotes Cdc42-induced actin polymerization for asymmetric division in oocytes

Polo-like kinase I (Plk1) is a highly conserved seronine/threonine kinase essential in meiosis and mitosis for spindle formation and cytokinesis. Here, through temporal application of Plk1 inhibitors, we identify a new role for Plk1 in the establishment of cortical polarity essential for highly asym...

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Detalles Bibliográficos
Autores principales: Yuen, Wai Shan, Zhang, Qing Hua, Bourdais, Anne, Adhikari, Deepak, Halet, Guillaume, Carroll, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993042/
https://www.ncbi.nlm.nih.gov/pubmed/36883283
http://dx.doi.org/10.1098/rsob.220326

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