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Structure of the Ndc80 complex and its interactions at the yeast kinetochore–microtubule interface

The conserved Ndc80 kinetochore complex, Ndc80c, is the principal link between mitotic spindle microtubules and centromere-associated proteins. We used AlphaFold 2 (AF2) to obtain predictions of the Ndc80 ‘loop’ structure and of the Ndc80 : Nuf2 globular head domains that interact with the Dam1 subu...

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Detalles Bibliográficos
Autores principales:	Zahm, Jacob A., Jenni, Simon, Harrison, Stephen C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993044/ https://www.ncbi.nlm.nih.gov/pubmed/36883282 http://dx.doi.org/10.1098/rsob.220378

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