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Extreme value modelling of SARS-CoV-2 community transmission using discrete generalized Pareto distributions

Superspreading has been suggested to be a major driver of overall transmission in the case of SARS-CoV-2. It is, therefore, important to statistically investigate the tail features of superspreading events (SSEs) to better understand virus propagation and control. Our extreme value analysis of diffe...

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Autores principales: Daouia, Abdelaati, Stupfler, Gilles, Usseglio-Carleve, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993046/
https://www.ncbi.nlm.nih.gov/pubmed/36908992
http://dx.doi.org/10.1098/rsos.220977
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author Daouia, Abdelaati
Stupfler, Gilles
Usseglio-Carleve, Antoine
author_facet Daouia, Abdelaati
Stupfler, Gilles
Usseglio-Carleve, Antoine
author_sort Daouia, Abdelaati
collection PubMed
description Superspreading has been suggested to be a major driver of overall transmission in the case of SARS-CoV-2. It is, therefore, important to statistically investigate the tail features of superspreading events (SSEs) to better understand virus propagation and control. Our extreme value analysis of different sources of secondary case data indicates that case numbers of SSEs associated with SARS-CoV-2 may be fat-tailed, although substantially less so than predicted recently in the literature, but also less important relative to SSEs associated with SARS-CoV. The results caution against pooling data from both coronaviruses. This could provide policy- and decision-makers with a more reliable assessment of the tail exposure to SARS-CoV-2 contamination. Going further, we consider the broader problem of large community transmission. We study the tail behaviour of SARS-CoV-2 cluster cases documented both in official reports and in the media. Our results suggest that the observed cluster sizes have been fat-tailed in the vast majority of surveyed countries. We also give estimates and confidence intervals of the extreme potential risk for those countries. A key component of our methodology is up-to-date discrete generalized Pareto models which allow for maximum likelihood-based inference of data with a high degree of discreteness.
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spelling pubmed-99930462023-03-09 Extreme value modelling of SARS-CoV-2 community transmission using discrete generalized Pareto distributions Daouia, Abdelaati Stupfler, Gilles Usseglio-Carleve, Antoine R Soc Open Sci Mathematics Superspreading has been suggested to be a major driver of overall transmission in the case of SARS-CoV-2. It is, therefore, important to statistically investigate the tail features of superspreading events (SSEs) to better understand virus propagation and control. Our extreme value analysis of different sources of secondary case data indicates that case numbers of SSEs associated with SARS-CoV-2 may be fat-tailed, although substantially less so than predicted recently in the literature, but also less important relative to SSEs associated with SARS-CoV. The results caution against pooling data from both coronaviruses. This could provide policy- and decision-makers with a more reliable assessment of the tail exposure to SARS-CoV-2 contamination. Going further, we consider the broader problem of large community transmission. We study the tail behaviour of SARS-CoV-2 cluster cases documented both in official reports and in the media. Our results suggest that the observed cluster sizes have been fat-tailed in the vast majority of surveyed countries. We also give estimates and confidence intervals of the extreme potential risk for those countries. A key component of our methodology is up-to-date discrete generalized Pareto models which allow for maximum likelihood-based inference of data with a high degree of discreteness. The Royal Society 2023-03-08 /pmc/articles/PMC9993046/ /pubmed/36908992 http://dx.doi.org/10.1098/rsos.220977 Text en © 2023 The Authors. https://creativecommons.org/licenses/by/4.0/Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, provided the original author and source are credited.
spellingShingle Mathematics
Daouia, Abdelaati
Stupfler, Gilles
Usseglio-Carleve, Antoine
Extreme value modelling of SARS-CoV-2 community transmission using discrete generalized Pareto distributions
title Extreme value modelling of SARS-CoV-2 community transmission using discrete generalized Pareto distributions
title_full Extreme value modelling of SARS-CoV-2 community transmission using discrete generalized Pareto distributions
title_fullStr Extreme value modelling of SARS-CoV-2 community transmission using discrete generalized Pareto distributions
title_full_unstemmed Extreme value modelling of SARS-CoV-2 community transmission using discrete generalized Pareto distributions
title_short Extreme value modelling of SARS-CoV-2 community transmission using discrete generalized Pareto distributions
title_sort extreme value modelling of sars-cov-2 community transmission using discrete generalized pareto distributions
topic Mathematics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993046/
https://www.ncbi.nlm.nih.gov/pubmed/36908992
http://dx.doi.org/10.1098/rsos.220977
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