Establishment of an in vitro Differentiation and Dedifferentiation System of Rat Schwann Cells

In the peripheral nervous system, Schwann cells are the primary type of glia; their in vitro differentiation and dedifferentiation system has not been described in detail in the literature. Thus, an in vitro differentiation and dedifferentiation system of rat Schwann cells is described in this proto...

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Detalles Bibliográficos
Autor principal: Zou, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bio-Protocol 2023
Materias:
Methods Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993079/
https://www.ncbi.nlm.nih.gov/pubmed/36908636
http://dx.doi.org/10.21769/BioProtoc.4631
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author Zou, Ying
author_facet Zou, Ying
author_sort Zou, Ying
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description In the peripheral nervous system, Schwann cells are the primary type of glia; their in vitro differentiation and dedifferentiation system has not been described in detail in the literature. Thus, an in vitro differentiation and dedifferentiation system of rat Schwann cells is described in this protocol. These cultures and systems may be used to investigate the morphological and biochemical effects of drug interventions or lentivirus-mediated gene transfer on Schwann cells during differentiation or dedifferentiation. Graphical abstract [Image: see text]
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spelling pubmed-99930792023-03-09 Establishment of an in vitro Differentiation and Dedifferentiation System of Rat Schwann Cells Zou, Ying Bio Protoc Methods Article In the peripheral nervous system, Schwann cells are the primary type of glia; their in vitro differentiation and dedifferentiation system has not been described in detail in the literature. Thus, an in vitro differentiation and dedifferentiation system of rat Schwann cells is described in this protocol. These cultures and systems may be used to investigate the morphological and biochemical effects of drug interventions or lentivirus-mediated gene transfer on Schwann cells during differentiation or dedifferentiation. Graphical abstract [Image: see text] Bio-Protocol 2023-03-05 /pmc/articles/PMC9993079/ /pubmed/36908636 http://dx.doi.org/10.21769/BioProtoc.4631 Text en Copyright © 2023 The Authors; exclusive licensee Bio-protocol LLC. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the CC BY-NC license (https://creativecommons.org/licenses/by-nc/4.0/).
spellingShingle Methods Article
Zou, Ying
Establishment of an in vitro Differentiation and Dedifferentiation System of Rat Schwann Cells
title Establishment of an in vitro Differentiation and Dedifferentiation System of Rat Schwann Cells
title_full Establishment of an in vitro Differentiation and Dedifferentiation System of Rat Schwann Cells
title_fullStr Establishment of an in vitro Differentiation and Dedifferentiation System of Rat Schwann Cells
title_full_unstemmed Establishment of an in vitro Differentiation and Dedifferentiation System of Rat Schwann Cells
title_short Establishment of an in vitro Differentiation and Dedifferentiation System of Rat Schwann Cells
title_sort establishment of an in vitro differentiation and dedifferentiation system of rat schwann cells
topic Methods Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993079/
https://www.ncbi.nlm.nih.gov/pubmed/36908636
http://dx.doi.org/10.21769/BioProtoc.4631
work_keys_str_mv AT zouying establishmentofaninvitrodifferentiationanddedifferentiationsystemofratschwanncells

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