Investigation of 13q14.3 deletion by cytogenetic analysis and FISH technique and miRNA-15a and miRNA-16-1 by real time PCR in chronic lymphocytic leukemia

BACKGROUND: The most frequent cytogenetic aberration is 13q14.3 deletion in Chronic Lymphocytic Leukemia (CLL). HsamiR-15a/hsa-miR-16-1 are tumor suppressor miRNAs encoded from 13q14.3 region. OBJECTIVES: The aim of this study was to investigate the 13q14.3 deletion using molecular and cytogenetic t...

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Autores principales: Yılmaz, Melike, Kuru, R Dilhan, Erdoğan, Isil, Soysal, Teoman, Hacıhanefioglu, Seniha, Baykara, Onur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Makerere Medical School 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993287/
https://www.ncbi.nlm.nih.gov/pubmed/36910369
http://dx.doi.org/10.4314/ahs.v22i3.20

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