Aspergillus-specific IgM/IgG antibody serostatus of patients hospitalized with moderate-critical COVID-19 in Uganda

Invasive pulmonary aspergillosis is known to complicate the coronavirus diseases-2019 (COVID-19), especially those with critical illness. We investigated the baseline anti-Aspergillus antibody serostatus of patients with moderate-critical COVID-19 hospitalized at 3 COVID-19 Treatment Units in Uganda...

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Detalles Bibliográficos
Autores principales: Bongomin, Felix, Kwizera, Richard, Mande, Emmanuel, Aloyo, Sharley Melissa, Achan, Beatrice, Namusobya, Martha, Sereke, Senai Goitom, Batte, Charles, Kiguli, Sarah, Baluku, Joseph Baruch, Joloba, Moses L, Kirenga, Bruce J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Makerere Medical School 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993298/
https://www.ncbi.nlm.nih.gov/pubmed/36910368
http://dx.doi.org/10.4314/ahs.v22i3.54
Descripción
Sumario:Invasive pulmonary aspergillosis is known to complicate the coronavirus diseases-2019 (COVID-19), especially those with critical illness. We investigated the baseline anti-Aspergillus antibody serostatus of patients with moderate-critical COVID-19 hospitalized at 3 COVID-19 Treatment Units in Uganda. All 46 tested patients, mean age 30, and 11% with underlying respiratory disease had a negative serum anti-Aspergillus IgM/IgG antibody immunochromatographic test on day 3 (mean) of symptom onset (range 1–26), but follow up specimens to assess seroconversion were not available.

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