Aspergillus-specific IgM/IgG antibody serostatus of patients hospitalized with moderate-critical COVID-19 in Uganda

Invasive pulmonary aspergillosis is known to complicate the coronavirus diseases-2019 (COVID-19), especially those with critical illness. We investigated the baseline anti-Aspergillus antibody serostatus of patients with moderate-critical COVID-19 hospitalized at 3 COVID-19 Treatment Units in Uganda...

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Autores principales: Bongomin, Felix, Kwizera, Richard, Mande, Emmanuel, Aloyo, Sharley Melissa, Achan, Beatrice, Namusobya, Martha, Sereke, Senai Goitom, Batte, Charles, Kiguli, Sarah, Baluku, Joseph Baruch, Joloba, Moses L, Kirenga, Bruce J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Makerere Medical School 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993298/
https://www.ncbi.nlm.nih.gov/pubmed/36910368
http://dx.doi.org/10.4314/ahs.v22i3.54
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author Bongomin, Felix
Kwizera, Richard
Mande, Emmanuel
Aloyo, Sharley Melissa
Achan, Beatrice
Namusobya, Martha
Sereke, Senai Goitom
Batte, Charles
Kiguli, Sarah
Baluku, Joseph Baruch
Joloba, Moses L
Kirenga, Bruce J
author_facet Bongomin, Felix
Kwizera, Richard
Mande, Emmanuel
Aloyo, Sharley Melissa
Achan, Beatrice
Namusobya, Martha
Sereke, Senai Goitom
Batte, Charles
Kiguli, Sarah
Baluku, Joseph Baruch
Joloba, Moses L
Kirenga, Bruce J
author_sort Bongomin, Felix
collection PubMed
description Invasive pulmonary aspergillosis is known to complicate the coronavirus diseases-2019 (COVID-19), especially those with critical illness. We investigated the baseline anti-Aspergillus antibody serostatus of patients with moderate-critical COVID-19 hospitalized at 3 COVID-19 Treatment Units in Uganda. All 46 tested patients, mean age 30, and 11% with underlying respiratory disease had a negative serum anti-Aspergillus IgM/IgG antibody immunochromatographic test on day 3 (mean) of symptom onset (range 1–26), but follow up specimens to assess seroconversion were not available.
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spelling pubmed-99932982023-03-09 Aspergillus-specific IgM/IgG antibody serostatus of patients hospitalized with moderate-critical COVID-19 in Uganda Bongomin, Felix Kwizera, Richard Mande, Emmanuel Aloyo, Sharley Melissa Achan, Beatrice Namusobya, Martha Sereke, Senai Goitom Batte, Charles Kiguli, Sarah Baluku, Joseph Baruch Joloba, Moses L Kirenga, Bruce J Afr Health Sci Articles Invasive pulmonary aspergillosis is known to complicate the coronavirus diseases-2019 (COVID-19), especially those with critical illness. We investigated the baseline anti-Aspergillus antibody serostatus of patients with moderate-critical COVID-19 hospitalized at 3 COVID-19 Treatment Units in Uganda. All 46 tested patients, mean age 30, and 11% with underlying respiratory disease had a negative serum anti-Aspergillus IgM/IgG antibody immunochromatographic test on day 3 (mean) of symptom onset (range 1–26), but follow up specimens to assess seroconversion were not available. Makerere Medical School 2022-09 /pmc/articles/PMC9993298/ /pubmed/36910368 http://dx.doi.org/10.4314/ahs.v22i3.54 Text en © 2022 Bongomin F et al. https://creativecommons.org/licenses/by/4.0/Licensee African Health Sciences. This is an Open Access article distributed under the terms of the Creative commons Attribution License (https://creativecommons.org/licenses/BY/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Bongomin, Felix
Kwizera, Richard
Mande, Emmanuel
Aloyo, Sharley Melissa
Achan, Beatrice
Namusobya, Martha
Sereke, Senai Goitom
Batte, Charles
Kiguli, Sarah
Baluku, Joseph Baruch
Joloba, Moses L
Kirenga, Bruce J
Aspergillus-specific IgM/IgG antibody serostatus of patients hospitalized with moderate-critical COVID-19 in Uganda
title Aspergillus-specific IgM/IgG antibody serostatus of patients hospitalized with moderate-critical COVID-19 in Uganda
title_full Aspergillus-specific IgM/IgG antibody serostatus of patients hospitalized with moderate-critical COVID-19 in Uganda
title_fullStr Aspergillus-specific IgM/IgG antibody serostatus of patients hospitalized with moderate-critical COVID-19 in Uganda
title_full_unstemmed Aspergillus-specific IgM/IgG antibody serostatus of patients hospitalized with moderate-critical COVID-19 in Uganda
title_short Aspergillus-specific IgM/IgG antibody serostatus of patients hospitalized with moderate-critical COVID-19 in Uganda
title_sort aspergillus-specific igm/igg antibody serostatus of patients hospitalized with moderate-critical covid-19 in uganda
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993298/
https://www.ncbi.nlm.nih.gov/pubmed/36910368
http://dx.doi.org/10.4314/ahs.v22i3.54
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