miR-34a/DRP-1-mediated mitophagy participated in cisplatin-induced ototoxicity via increasing oxidative stress

PURPOSE: Cisplatin is a widely used and effective chemotherapeutic agent for most solid malignant tumors. However, cisplatin-induced ototoxicity is a common adverse effect that limits the therapeutic efficacy of tumors in the clinic. To date, the specific mechanism of ototoxicity has not been fully...

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Detalles Bibliográficos
Autores principales: Wang, Haiyan, Lin, Hanqing, Kang, Weibiao, Huang, Lingfei, Gong, Sisi, Zhang, Tao, Huang, Xiaotong, He, Feinan, Ye, Yongyi, Tang, Yiyang, Jia, Haiying, Yang, Haidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993635/
https://www.ncbi.nlm.nih.gov/pubmed/36882858
http://dx.doi.org/10.1186/s40360-023-00654-1

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