Cargando…

An agent-based approach for modelling and simulation of glycoprotein VI receptor diffusion, localisation and dimerisation in platelet lipid rafts

Receptor diffusion plays an essential role in cellular signalling via the plasma membrane microenvironment and receptor interactions, but the regulation is not well understood. To aid in understanding of the key determinants of receptor diffusion and signalling, we developed agent-based models (ABMs...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tantiwong, Chukiat, Dunster, Joanne L., Cavill, Rachel, Tomlinson, Michael G., Wierling, Christoph, Heemskerk, Johan W. M., Gibbins, Jonathan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994409/ https://www.ncbi.nlm.nih.gov/pubmed/36890261 http://dx.doi.org/10.1038/s41598-023-30884-6

Ejemplares similares

Regulation of Glycoprotein VI-Dependent Platelet Activation and Thrombus Formation by Heparan Sulfate Proteoglycan Perlecan
por: Provenzale, Isabella, et al.
Publicado: (2023)

Platelet GPVI (Glycoprotein VI) and Thrombotic Complications in the Venous System
por: Perrella, Gina, et al.
Publicado: (2021)

Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces
por: Jooss, Natalie J., et al.
Publicado: (2019)

Long-term platelet priming after glycoprotein VI stimulation in comparison to Protease-Activating Receptor (PAR) stimulation
por: Zou, Jinmi, et al.
Publicado: (2021)

Role of heat shock protein 47 in platelet glycoprotein VI dimerization and signaling
por: AlOuda, Sarah K., et al.
Publicado: (2023)

Platelet surface receptor glycoprotein VI-dimer is overexpressed in stroke: The Glycoprotein VI in Stroke (GYPSIE) study results
por: Induruwa, Isuru, et al.
Publicado: (2022)

Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation
por: Dunster, Joanne L., et al.
Publicado: (2019)

Visible light-induced thymine dimerisation based on large localised field gradient by non-uniform optical near-field
por: Tate, Naoya, et al.
Publicado: (2019)

Dimerisation of the Drosophila odorant coreceptor Orco
por: Mukunda, Latha, et al.
Publicado: (2014)

Immobilized fibrinogen activates human platelets through glycoprotein VI
por: Mangin, Pierre H, et al.
Publicado: (2018)

Diboramacrocycles: reversible borole dimerisation–dissociation systems
por: Fuchs, Sonja, et al.
Publicado: (2022)

Minimal Collagen-Binding Epitope of Glycoprotein VI in Human and Mouse Platelets
por: Han, Chao, et al.
Publicado: (2023)

Long-Term Antithrombotic Protection by in Vivo Depletion of Platelet Glycoprotein VI in Mice
por: Nieswandt, Bernhard, et al.
Publicado: (2001)

Glycoprotein VI Gene Variants Affect Pregnancy Loss in Patients With Platelet Hyperaggregability
por: Sokol, Juraj, et al.
Publicado: (2018)

Localization of the Adhesion Receptor Glycoprotein Ib-IX-V Complex to Lipid Rafts Is Required for Platelet Adhesion and Activation
por: Shrimpton, Corie N., et al.
Publicado: (2002)

Lipid phosphate phosphatases dimerise, but this interaction is not required for in vivo activity
por: Burnett, Camilla, et al.
Publicado: (2004)

Different dimerisation mode for TLR4 upon endosomal acidification?
por: Gangloff, Monique
Publicado: (2012)

Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin
por: Cheng, Mu, et al.
Publicado: (2014)

Modelling the influence of dimerisation sequence dissimilarities on the auxin signalling network
por: Legrand, Jonathan, et al.
Publicado: (2016)

A Crucial Role of Glycoprotein VI for Platelet Recruitment to the Injured Arterial Wall In Vivo
por: Massberg, Steffen, et al.
Publicado: (2003)

Collagen Can Selectively Trigger a Platelet Secretory Phenotype via Glycoprotein VI
por: Ollivier, Véronique, et al.
Publicado: (2014)

Inhibition of Btk by Btk-specific concentrations of ibrutinib and acalabrutinib delays but does not block platelet aggregation mediated by glycoprotein VI
por: Nicolson, Phillip L.R., et al.
Publicado: (2018)

Exploring the constituent mechanisms of hepatitis: a dynamical systems approach
por: Dunster, Joanne L, et al.
Publicado: (2022)

Correction: Lipid phosphate phosphatases dimerise, but this interaction is not required for in vivo activity
por: Burnett, C, et al.
Publicado: (2005)

Dimerisation, rhodium complex formation and rearrangements of N-heterocyclic carbenes of indazoles
por: Guan, Zong, et al.
Publicado: (2014)

Pressure-induced magnetic transitions with change of the orbital configuration in dimerised systems
por: Korotin, Dmitry M., et al.
Publicado: (2016)

New insights into GPCR coupling and dimerisation from cryo-EM structures
por: Gusach, Anastasiia, et al.
Publicado: (2023)

Function of Platelet Glycosphingolipid Microdomains/Lipid Rafts
por: Komatsuya, Keisuke, et al.
Publicado: (2020)

Assessment of a complete and classified platelet proteome from genome-wide transcripts of human platelets and megakaryocytes covering platelet functions
por: Huang, Jingnan, et al.
Publicado: (2021)

An extensive endoplasmic reticulum-localised glycoprotein family in trypanosomatids
por: Allison, Harriet, et al.
Publicado: (2014)

Constitutive Dimerization of Glycoprotein VI (GPVI) in Resting Platelets Is Essential for Binding to Collagen and Activation in Flowing Blood
por: Jung, Stephanie M., et al.
Publicado: (2012)

Exacerbation of Glycoprotein VI-Dependent Platelet Responses in a Rhesus Monkey Model of Type 1 Diabetes
por: Arthur, J. F., et al.
Publicado: (2013)

Platelet Receptor Glycoprotein VI-Dimer Is Overexpressed in Patients with Atrial Fibrillation at High Risk of Ischemic Stroke
por: Induruwa, Isuru, et al.
Publicado: (2023)

Multiparameter phenotyping of platelet reactivity for stratification of human cohorts
por: Dunster, Joanne L., et al.
Publicado: (2021)

The C313Y Piedmontese mutation decreases myostatin covalent dimerisation and stability
por: Starck, Carlene S, et al.
Publicado: (2011)

Inherent Structural Disorder and Dimerisation of Murine Norovirus NS1-2 Protein
por: Baker, Estelle S., et al.
Publicado: (2012)

Dimerisation of the Yeast K(+) Translocation Protein Trk1 Depends on the K(+) Concentration
por: Kulik, Natalia, et al.
Publicado: (2022)

Experimental validation of computerised models of clustering of platelet glycoprotein receptors that signal via tandem SH2 domain proteins
por: Maqsood, Zahra, et al.
Publicado: (2022)

Characterisation of Platelet Sensitivity in Severe COVID-19
por: Saputil, Rocel C., et al.
Publicado: (2022)

Inhibition of Glycoprotein VI Clustering by Collagen as a Mechanism of Inhibiting Collagen-Induced Platelet Responses: The Example of Losartan
por: Jiang, Peng, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_rtpuub8alqcsc600inslbg7k9t