PROTACs: Walking through hematological malignancies

Proteolysis targeting chimeras (PROTACs) are heterobifunctional small molecules that uses the proteasome ubiquitin system to target proteins of interest and promote their degradation with remarkable selectivity. Importantly, unlike conventional small molecule inhibitors, PROTACs have proven highly e...

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Detalles Bibliográficos
Autores principales: Bou Malhab, Lara J., Alsafar, Habiba, Ibrahim, Saleh, Rahmani, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994433/
https://www.ncbi.nlm.nih.gov/pubmed/36909156
http://dx.doi.org/10.3389/fphar.2023.1086946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994433/
https://www.ncbi.nlm.nih.gov/pubmed/36909156
http://dx.doi.org/10.3389/fphar.2023.1086946

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