Mutated axon guidance gene PLXNB2 sustains growth and invasiveness of stem cells isolated from cancers of unknown primary

The genetic changes sustaining the development of cancers of unknown primary (CUP) remain elusive. The whole‐exome genomic profiling of 14 rigorously selected CUP samples did not reveal specific recurring mutation in known driver genes. However, by comparing the mutational landscape of CUPs with tha...

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Detalles Bibliográficos
Autores principales: Brundu, Serena, Napolitano, Virginia, Franzolin, Giulia, Lo Cascio, Ettore, Mastrantonio, Roberta, Sardo, Gabriele, Cascardi, Eliano, Verginelli, Federica, Sarnataro, Sergio, Gambardella, Gennaro, Pisacane, Alberto, Arcovito, Alessandro, Boccaccio, Carla, Comoglio, Paolo M, Giraudo, Enrico, Tamagnone, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994481/
https://www.ncbi.nlm.nih.gov/pubmed/36722641
http://dx.doi.org/10.15252/emmm.202216104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994481/
https://www.ncbi.nlm.nih.gov/pubmed/36722641
http://dx.doi.org/10.15252/emmm.202216104

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