EGR1 drives cell proliferation by directly stimulating TFEB transcription in response to starvation

The stress-responsive transcription factor EB (TFEB) is a master controller of lysosomal biogenesis and autophagy and plays a major role in several cancer-associated diseases. TFEB is regulated at the posttranslational level by the nutrient-sensitive kinase complex mTORC1. However, little is known a...

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Detalles Bibliográficos
Autores principales: Cesana, Marcella, Tufano, Gennaro, Panariello, Francesco, Zampelli, Nicolina, Ambrosio, Susanna, De Cegli, Rossella, Mutarelli, Margherita, Vaccaro, Lorenzo, Ziller, Micheal J., Cacchiarelli, Davide, Medina, Diego L., Ballabio, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994711/
https://www.ncbi.nlm.nih.gov/pubmed/36888606
http://dx.doi.org/10.1371/journal.pbio.3002034

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