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Kidney absorbed radiation doses for [(177)Lu]Lu-PSMA-617 and [(177)Lu]Lu-PSMA-I&T determined by 3D clinical dosimetry

For prostate-specific membrane antigen-directed radioligand therapy (PSMA-RLT), [(177)Lu]Lu-PSMA-617 and [(177)Lu]Lu-PSMA-I&T are the currently preferred compounds. Recent preclinical studies suggested ~30x higher kidney absorbed dose for [(177)Lu]Lu-PSMA-I&T compared to [(177)Lu]Lu-PSMA-617...

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Detalles Bibliográficos
Autores principales: Uijen, Maike J.M., Privé, Bastiaan M., van Herpen, Carla M.L., Westdorp, Harm, van Gemert, Willemijn A., de Bakker, Maarten, Gotthardt, Martin, Konijnenberg, Mark W., Peters, Steffie M.B., Nagarajah, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994818/
https://www.ncbi.nlm.nih.gov/pubmed/36597884
http://dx.doi.org/10.1097/MNM.0000000000001658

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