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Ampicillin-controlled glucose metabolism manipulates the transition from tolerance to resistance in bacteria

The mechanism(s) of how bacteria acquire tolerance and then resistance to antibiotics remains poorly understood. Here, we show that glucose abundance decreases progressively as ampicillin-sensitive strains acquire resistance to ampicillin. The mechanism involves that ampicillin initiates this event...

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Detalles Bibliográficos
Autores principales: Jiang, Ming, Su, Yu-bin, Ye, Jin-zhou, Li, Hui, Kuang, Su-fang, Wu, Jia-han, Li, Shao-hua, Peng, Xuan-xian, Peng, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995076/
https://www.ncbi.nlm.nih.gov/pubmed/36888710
http://dx.doi.org/10.1126/sciadv.ade8582