Compartmentalization and persistence of dominant (regulatory) T cell clones indicates antigen skewing in juvenile idiopathic arthritis

Autoimmune inflammation is characterized by tissue infiltration and expansion of antigen-specific T cells. Although this inflammation is often limited to specific target tissues, it remains yet to be explored whether distinct affected sites are infiltrated with the same, persistent T cell clones. He...

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Detalles Bibliográficos
Autores principales: Mijnheer, Gerdien, Servaas, Nila Hendrika, Leong, Jing Yao, Boltjes, Arjan, Spierings, Eric, Chen, Phyllis, Lai, Liyun, Petrelli, Alessandra, Vastert, Sebastiaan, de Boer, Rob J, Albani, Salvatore, Pandit, Aridaman, van Wijk, Femke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995115/
https://www.ncbi.nlm.nih.gov/pubmed/36688525
http://dx.doi.org/10.7554/eLife.79016

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