Targeting the fatty acid binding proteins disrupts multiple myeloma cell cycle progression and MYC signaling

Multiple myeloma is an incurable plasma cell malignancy with only a 53% 5-year survival rate. There is a critical need to find new multiple myeloma vulnerabilities and therapeutic avenues. Herein, we identified and explored a novel multiple myeloma target: the fatty acid binding protein (FABP) famil...

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Detalles Bibliográficos
Autores principales: Farrell, Mariah, Fairfield, Heather, Karam, Michelle, D'Amico, Anastasia, Murphy, Connor S, Falank, Carolyne, Pistofidi, Romanos Sklavenitis, Cao, Amanda, Marinac, Catherine R, Dragon, Julie A, McGuinness, Lauren, Gartner, Carlos G, Iorio, Reagan Di, Jachimowicz, Edward, DeMambro, Victoria, Vary, Calvin, Reagan, Michaela R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995119/
https://www.ncbi.nlm.nih.gov/pubmed/36880649
http://dx.doi.org/10.7554/eLife.81184

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