Cargando…
Efficacy and safety of repeated endoscopic radial incision and cutting procedure for benign esophageal stricture
Background and study aims: Radial incision and cutting (RIC) is indicated for refractory benign esophageal strictures after curative treatment for esophageal cancer and has shown favorable short-term outcomes. However, re-stricture after RIC may occur in the long term, and RIC is performed repeatedl...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Georg Thieme Verlag KG
2023
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995178/ https://www.ncbi.nlm.nih.gov/pubmed/36910847 http://dx.doi.org/10.1055/a-2005-7678 |
_version_ | 1784902768114270208 |
---|---|
author | Kano, Yuki Kadota, Tomohiro Inaba, Atsushi Sunakawa, Hironori Takashima, Kenji Nakajo, Keiichiro Murano, Tatsuro Shinmura, Kensuke Yoda, Yusuke Ikematsu, Hiroaki Akimoto, Tetsuo Yano, Tomonori |
author_facet | Kano, Yuki Kadota, Tomohiro Inaba, Atsushi Sunakawa, Hironori Takashima, Kenji Nakajo, Keiichiro Murano, Tatsuro Shinmura, Kensuke Yoda, Yusuke Ikematsu, Hiroaki Akimoto, Tetsuo Yano, Tomonori |
author_sort | Kano, Yuki |
collection | PubMed |
description | Background and study aims: Radial incision and cutting (RIC) is indicated for refractory benign esophageal strictures after curative treatment for esophageal cancer and has shown favorable short-term outcomes. However, re-stricture after RIC may occur in the long term, and RIC is performed repeatedly in such cases, but the efficacy and safety of repeated RIC are unclear. Therefore, we aimed to demonstrate the efficacy and safety of the repeated RIC for refractory benign esophageal strictures after surgical and non-surgical treatment. Patients and methods: Between April 2008 and September 2019, we enrolled patients who were treated with the first RIC for benign esophageal strictures. The RIC was indicated for the refractory stricture and repeatedly performed for re-refractory esophageal stricture after RIC. We retrospectively evaluated the 6-month refractory stricture-free rate, and adverse events (AEs) in the first RIC and repeated RICs. Results: Forty-six patients (39 men, 7 women; median age, 71 years, range 49–85) were included. RIC was performed once in 24 patients (non-repeated RIC group) and two or more times in 22 patients (repeated RIC group). In all patients, the 6-month refractory stricture-free rate after the first RIC were 42.3 %. In the repeated RIC group, the 6-month refractory stricture-free rate after the first and repeated RICs were 18.2 % vs 18.2 %, respectively. No AEs were noted. Conclusions: Repeated RIC could be effective in the short-term and safe even for patients with refractory benign esophageal stricture after the first RIC. However, it cannot be considered curative treatment for refractory stricture because of poor long-term results. |
format | Online Article Text |
id | pubmed-9995178 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Georg Thieme Verlag KG |
record_format | MEDLINE/PubMed |
spelling | pubmed-99951782023-03-09 Efficacy and safety of repeated endoscopic radial incision and cutting procedure for benign esophageal stricture Kano, Yuki Kadota, Tomohiro Inaba, Atsushi Sunakawa, Hironori Takashima, Kenji Nakajo, Keiichiro Murano, Tatsuro Shinmura, Kensuke Yoda, Yusuke Ikematsu, Hiroaki Akimoto, Tetsuo Yano, Tomonori Endosc Int Open Background and study aims: Radial incision and cutting (RIC) is indicated for refractory benign esophageal strictures after curative treatment for esophageal cancer and has shown favorable short-term outcomes. However, re-stricture after RIC may occur in the long term, and RIC is performed repeatedly in such cases, but the efficacy and safety of repeated RIC are unclear. Therefore, we aimed to demonstrate the efficacy and safety of the repeated RIC for refractory benign esophageal strictures after surgical and non-surgical treatment. Patients and methods: Between April 2008 and September 2019, we enrolled patients who were treated with the first RIC for benign esophageal strictures. The RIC was indicated for the refractory stricture and repeatedly performed for re-refractory esophageal stricture after RIC. We retrospectively evaluated the 6-month refractory stricture-free rate, and adverse events (AEs) in the first RIC and repeated RICs. Results: Forty-six patients (39 men, 7 women; median age, 71 years, range 49–85) were included. RIC was performed once in 24 patients (non-repeated RIC group) and two or more times in 22 patients (repeated RIC group). In all patients, the 6-month refractory stricture-free rate after the first RIC were 42.3 %. In the repeated RIC group, the 6-month refractory stricture-free rate after the first and repeated RICs were 18.2 % vs 18.2 %, respectively. No AEs were noted. Conclusions: Repeated RIC could be effective in the short-term and safe even for patients with refractory benign esophageal stricture after the first RIC. However, it cannot be considered curative treatment for refractory stricture because of poor long-term results. Georg Thieme Verlag KG 2023-03-08 /pmc/articles/PMC9995178/ /pubmed/36910847 http://dx.doi.org/10.1055/a-2005-7678 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited. |
spellingShingle | Kano, Yuki Kadota, Tomohiro Inaba, Atsushi Sunakawa, Hironori Takashima, Kenji Nakajo, Keiichiro Murano, Tatsuro Shinmura, Kensuke Yoda, Yusuke Ikematsu, Hiroaki Akimoto, Tetsuo Yano, Tomonori Efficacy and safety of repeated endoscopic radial incision and cutting procedure for benign esophageal stricture |
title | Efficacy and safety of repeated endoscopic radial incision and cutting procedure for benign esophageal stricture |
title_full | Efficacy and safety of repeated endoscopic radial incision and cutting procedure for benign esophageal stricture |
title_fullStr | Efficacy and safety of repeated endoscopic radial incision and cutting procedure for benign esophageal stricture |
title_full_unstemmed | Efficacy and safety of repeated endoscopic radial incision and cutting procedure for benign esophageal stricture |
title_short | Efficacy and safety of repeated endoscopic radial incision and cutting procedure for benign esophageal stricture |
title_sort | efficacy and safety of repeated endoscopic radial incision and cutting procedure for benign esophageal stricture |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995178/ https://www.ncbi.nlm.nih.gov/pubmed/36910847 http://dx.doi.org/10.1055/a-2005-7678 |
work_keys_str_mv | AT kanoyuki efficacyandsafetyofrepeatedendoscopicradialincisionandcuttingprocedureforbenignesophagealstricture AT kadotatomohiro efficacyandsafetyofrepeatedendoscopicradialincisionandcuttingprocedureforbenignesophagealstricture AT inabaatsushi efficacyandsafetyofrepeatedendoscopicradialincisionandcuttingprocedureforbenignesophagealstricture AT sunakawahironori efficacyandsafetyofrepeatedendoscopicradialincisionandcuttingprocedureforbenignesophagealstricture AT takashimakenji efficacyandsafetyofrepeatedendoscopicradialincisionandcuttingprocedureforbenignesophagealstricture AT nakajokeiichiro efficacyandsafetyofrepeatedendoscopicradialincisionandcuttingprocedureforbenignesophagealstricture AT muranotatsuro efficacyandsafetyofrepeatedendoscopicradialincisionandcuttingprocedureforbenignesophagealstricture AT shinmurakensuke efficacyandsafetyofrepeatedendoscopicradialincisionandcuttingprocedureforbenignesophagealstricture AT yodayusuke efficacyandsafetyofrepeatedendoscopicradialincisionandcuttingprocedureforbenignesophagealstricture AT ikematsuhiroaki efficacyandsafetyofrepeatedendoscopicradialincisionandcuttingprocedureforbenignesophagealstricture AT akimototetsuo efficacyandsafetyofrepeatedendoscopicradialincisionandcuttingprocedureforbenignesophagealstricture AT yanotomonori efficacyandsafetyofrepeatedendoscopicradialincisionandcuttingprocedureforbenignesophagealstricture |