Interaction between maternal immune activation and peripubertal stress in rats: impact on cocaine addiction-like behaviour, morphofunctional brain parameters and striatal transcriptome

Substance use disorders are more prevalent in schizophrenia, but the causal links between both conditions remain unclear. Maternal immune activation (MIA) is associated with schizophrenia which may be triggered by stressful experiences during adolescence. Therefore, we used a double-hit rat model, c...

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Detalles Bibliográficos
Autores principales: Capellán, Roberto, Orihuel, Javier, Marcos, Alberto, Ucha, Marcos, Moreno-Fernández, Mario, Casquero-Veiga, Marta, Soto-Montenegro, María Luisa, Desco, Manuel, Oteo-Vives, Marta, Ibáñez-Moragues, Marta, Magro-Calvo, Natalia, Morcillo, Miguel Ángel, Ambrosio, Emilio, Higuera-Matas, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995324/
https://www.ncbi.nlm.nih.gov/pubmed/36890154
http://dx.doi.org/10.1038/s41398-023-02378-6

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