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Unmet needs in ANCA-associated vasculitis: Physicians’ and patients’ perspectives
In recent years, clinical research has increased significantly and therapies for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis have improved. However, there are still unanswered questions and unmet needs about AAV patients. The purpose of this review is to examine the frontiers of...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995379/ https://www.ncbi.nlm.nih.gov/pubmed/36911748 http://dx.doi.org/10.3389/fimmu.2023.1112899 |
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author | Quartuccio, Luca Treppo, Elena Urso, Livio Del Frate, Giulia Mescia, Federica Alberici, Federico Vaglio, Augusto Emmi, Giacomo |
author_facet | Quartuccio, Luca Treppo, Elena Urso, Livio Del Frate, Giulia Mescia, Federica Alberici, Federico Vaglio, Augusto Emmi, Giacomo |
author_sort | Quartuccio, Luca |
collection | PubMed |
description | In recent years, clinical research has increased significantly and therapies for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis have improved. However, there are still unanswered questions and unmet needs about AAV patients. The purpose of this review is to examine the frontiers of research related to emerging biomarkers eventually predicting relapse, and new therapeutic approaches, not to mention new quality of life assessment tools. Identifying predictors of relapse may help optimize therapeutic strategies, minimize disease recurrence, and reduce treatment-related side effects. In addition, it is important to recognize that patients may suffer long-term consequences of the disease and its treatment, which, although life-saving, is often associated with significant side effects. Our goal, therefore, is to highlight what has been achieved, the pitfalls, and what still needs to be done, comparing the views of physicians and patients. |
format | Online Article Text |
id | pubmed-9995379 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-99953792023-03-10 Unmet needs in ANCA-associated vasculitis: Physicians’ and patients’ perspectives Quartuccio, Luca Treppo, Elena Urso, Livio Del Frate, Giulia Mescia, Federica Alberici, Federico Vaglio, Augusto Emmi, Giacomo Front Immunol Immunology In recent years, clinical research has increased significantly and therapies for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis have improved. However, there are still unanswered questions and unmet needs about AAV patients. The purpose of this review is to examine the frontiers of research related to emerging biomarkers eventually predicting relapse, and new therapeutic approaches, not to mention new quality of life assessment tools. Identifying predictors of relapse may help optimize therapeutic strategies, minimize disease recurrence, and reduce treatment-related side effects. In addition, it is important to recognize that patients may suffer long-term consequences of the disease and its treatment, which, although life-saving, is often associated with significant side effects. Our goal, therefore, is to highlight what has been achieved, the pitfalls, and what still needs to be done, comparing the views of physicians and patients. Frontiers Media S.A. 2023-02-23 /pmc/articles/PMC9995379/ /pubmed/36911748 http://dx.doi.org/10.3389/fimmu.2023.1112899 Text en Copyright © 2023 Quartuccio, Treppo, Urso, Del Frate, Mescia, Alberici, Vaglio and Emmi https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Immunology Quartuccio, Luca Treppo, Elena Urso, Livio Del Frate, Giulia Mescia, Federica Alberici, Federico Vaglio, Augusto Emmi, Giacomo Unmet needs in ANCA-associated vasculitis: Physicians’ and patients’ perspectives |
title | Unmet needs in ANCA-associated vasculitis: Physicians’ and patients’ perspectives |
title_full | Unmet needs in ANCA-associated vasculitis: Physicians’ and patients’ perspectives |
title_fullStr | Unmet needs in ANCA-associated vasculitis: Physicians’ and patients’ perspectives |
title_full_unstemmed | Unmet needs in ANCA-associated vasculitis: Physicians’ and patients’ perspectives |
title_short | Unmet needs in ANCA-associated vasculitis: Physicians’ and patients’ perspectives |
title_sort | unmet needs in anca-associated vasculitis: physicians’ and patients’ perspectives |
topic | Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995379/ https://www.ncbi.nlm.nih.gov/pubmed/36911748 http://dx.doi.org/10.3389/fimmu.2023.1112899 |
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