Postoperative residual neuromuscular block in a woman with severe preeclampsia treated with magnesium sulfate and nicardipine: A case report and literature review

Calcium channel blockers and magnesium sulfate are frequently used together, particularly in women with underlying chronic hypertension and pre-eclampsia. A review of the literature showed prolonged neuromuscular blockade after treatment with magnesium sulfate. Since magnesium and calcium have oppos...

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Autores principales: Song, Yingcai, Qian, Xiaozhe, Du, Weijia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Surgery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995428/
https://www.ncbi.nlm.nih.gov/pubmed/36911609
http://dx.doi.org/10.3389/fsurg.2023.1093969
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author Song, Yingcai
Qian, Xiaozhe
Du, Weijia
author_facet Song, Yingcai
Qian, Xiaozhe
Du, Weijia
author_sort Song, Yingcai
collection PubMed
description Calcium channel blockers and magnesium sulfate are frequently used together, particularly in women with underlying chronic hypertension and pre-eclampsia. A review of the literature showed prolonged neuromuscular blockade after treatment with magnesium sulfate. Since magnesium and calcium have opposite effects on the neuromuscular junctions, muscle weakness may become a postoperative manifestation of magnesium sulfate and calcium antagonist treatment in the obstetric population; however, limited information is available regarding this postulation. Here, we report a case wherein rocuronium activity was markedly prolonged due to pretreatment with magnesium sulfate and nicardipine after general anesthesia during an emergency cesarean delivery.
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spelling pubmed-99954282023-03-10 Postoperative residual neuromuscular block in a woman with severe preeclampsia treated with magnesium sulfate and nicardipine: A case report and literature review Song, Yingcai Qian, Xiaozhe Du, Weijia Front Surg Surgery Calcium channel blockers and magnesium sulfate are frequently used together, particularly in women with underlying chronic hypertension and pre-eclampsia. A review of the literature showed prolonged neuromuscular blockade after treatment with magnesium sulfate. Since magnesium and calcium have opposite effects on the neuromuscular junctions, muscle weakness may become a postoperative manifestation of magnesium sulfate and calcium antagonist treatment in the obstetric population; however, limited information is available regarding this postulation. Here, we report a case wherein rocuronium activity was markedly prolonged due to pretreatment with magnesium sulfate and nicardipine after general anesthesia during an emergency cesarean delivery. Frontiers Media S.A. 2023-02-23 /pmc/articles/PMC9995428/ /pubmed/36911609 http://dx.doi.org/10.3389/fsurg.2023.1093969 Text en © 2023 Song, Qian and Du. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Song, Yingcai
Qian, Xiaozhe
Du, Weijia
Postoperative residual neuromuscular block in a woman with severe preeclampsia treated with magnesium sulfate and nicardipine: A case report and literature review
title Postoperative residual neuromuscular block in a woman with severe preeclampsia treated with magnesium sulfate and nicardipine: A case report and literature review
title_full Postoperative residual neuromuscular block in a woman with severe preeclampsia treated with magnesium sulfate and nicardipine: A case report and literature review
title_fullStr Postoperative residual neuromuscular block in a woman with severe preeclampsia treated with magnesium sulfate and nicardipine: A case report and literature review
title_full_unstemmed Postoperative residual neuromuscular block in a woman with severe preeclampsia treated with magnesium sulfate and nicardipine: A case report and literature review
title_short Postoperative residual neuromuscular block in a woman with severe preeclampsia treated with magnesium sulfate and nicardipine: A case report and literature review
title_sort postoperative residual neuromuscular block in a woman with severe preeclampsia treated with magnesium sulfate and nicardipine: a case report and literature review
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995428/
https://www.ncbi.nlm.nih.gov/pubmed/36911609
http://dx.doi.org/10.3389/fsurg.2023.1093969
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AT qianxiaozhe postoperativeresidualneuromuscularblockinawomanwithseverepreeclampsiatreatedwithmagnesiumsulfateandnicardipineacasereportandliteraturereview
AT duweijia postoperativeresidualneuromuscularblockinawomanwithseverepreeclampsiatreatedwithmagnesiumsulfateandnicardipineacasereportandliteraturereview

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