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An improved total synthesis of tunicamycin V
The tunicamycins are important biochemical tools to study N-linked glycosylation and protein misfolding in cancer biochemistry fields. We reported a convergent synthesis of tunicamycin V with 21% overall yield from D-galactal. We have further optimized our original synthetic scheme by increasing the...
Autores principales: | Mitachi, Katsuhiko, Mingle, David, Kurosu, Michio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995453/ https://www.ncbi.nlm.nih.gov/pubmed/36911209 http://dx.doi.org/10.1016/j.mex.2023.102095 |
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