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An improved total synthesis of tunicamycin V

The tunicamycins are important biochemical tools to study N-linked glycosylation and protein misfolding in cancer biochemistry fields. We reported a convergent synthesis of tunicamycin V with 21% overall yield from D-galactal. We have further optimized our original synthetic scheme by increasing the...

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Detalles Bibliográficos
Autores principales: Mitachi, Katsuhiko, Mingle, David, Kurosu, Michio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995453/
https://www.ncbi.nlm.nih.gov/pubmed/36911209
http://dx.doi.org/10.1016/j.mex.2023.102095

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