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Size limits the sensitivity of kinetic schemes
Living things benefit from exquisite molecular sensitivity in many of their key processes, including DNA replication, transcription and translation, chemical sensing, and morphogenesis. At thermodynamic equilibrium, the basic biophysical mechanism for sensitivity is cooperative binding, for which it...
Autores principales: | Owen, Jeremy A., Horowitz, Jordan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995461/ https://www.ncbi.nlm.nih.gov/pubmed/36890153 http://dx.doi.org/10.1038/s41467-023-36705-8 |
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