Human PARP1 substrates and regulators of its catalytic activity: An updated overview

Poly (ADP-ribose) polymerase 1 (PARP1) is a key DNA damage sensor that is recruited to damaged sites after DNA strand breaks to initiate DNA repair. This is achieved by catalyzing attachment of ADP-ribose moieties, which are donated from NAD(+), on the amino acid residues of itself or other acceptor...

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Detalles Bibliográficos
Autores principales: Zhu, Tao, Zheng, Ju-Yan, Huang, Ling-Ling, Wang, Yan-Hong, Yao, Di-Fei, Dai, Hai-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995695/
https://www.ncbi.nlm.nih.gov/pubmed/36909172
http://dx.doi.org/10.3389/fphar.2023.1137151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995695/
https://www.ncbi.nlm.nih.gov/pubmed/36909172
http://dx.doi.org/10.3389/fphar.2023.1137151

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