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Human PARP1 substrates and regulators of its catalytic activity: An updated overview
Poly (ADP-ribose) polymerase 1 (PARP1) is a key DNA damage sensor that is recruited to damaged sites after DNA strand breaks to initiate DNA repair. This is achieved by catalyzing attachment of ADP-ribose moieties, which are donated from NAD(+), on the amino acid residues of itself or other acceptor...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995695/ https://www.ncbi.nlm.nih.gov/pubmed/36909172 http://dx.doi.org/10.3389/fphar.2023.1137151 |