Bruton’s tyrosine kinase inhibition attenuates disease progression by reducing renal immune cell invasion in mice with hemolytic-uremic syndrome

Hemolytic-uremic syndrome (HUS) can occur as a complication of an infection with Shiga-toxin (Stx)-producing Escherichia coli. Patients typically present with acute kidney injury, microangiopathic hemolytic anemia and thrombocytopenia. There is evidence that Stx-induced renal damage propagates a pro...

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Detalles Bibliográficos
Autores principales: Kröller, Sarah, Wissuwa, Bianka, Dennhardt, Sophie, Krieg, Nadine, Thiemermann, Christoph, Daniel, Christoph, Amann, Kerstin, Gunzer, Florian, Coldewey, Sina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995712/
https://www.ncbi.nlm.nih.gov/pubmed/36911665
http://dx.doi.org/10.3389/fimmu.2023.1105181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995712/
https://www.ncbi.nlm.nih.gov/pubmed/36911665
http://dx.doi.org/10.3389/fimmu.2023.1105181

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