Pro-and Antioxidant Status in Newborn with COVID-19

There is practically no information on the state of oxidative stress reactions in newborns with coronavirus infections. At the same time, such studies are extremely important and can contribute to better understanding of the process of reactivity in patients of different ages. The content of pro- an...

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Detalles Bibliográficos
Autores principales: Rychkova, L. V., Darenskaya, M. A., Petrova, A. G., Semenova, N. V., Moskaleva, E. V., Kolesnikov, S. I., Vanyarkina, A. S., Kolesnikova, L. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Virology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995714/
https://www.ncbi.nlm.nih.gov/pubmed/36892671
http://dx.doi.org/10.1007/s10517-023-05730-4
Descripción
Sumario:There is practically no information on the state of oxidative stress reactions in newborns with coronavirus infections. At the same time, such studies are extremely important and can contribute to better understanding of the process of reactivity in patients of different ages. The content of pro- and antioxidant status indicators was assessed in 44 newborns with confirmed COVID-19. It was found that the content of compounds with unsaturated double bonds, primary, secondary, and final LPO products were elevated in newborns with COVID-19. These changes were accompanied by higher SOD activity and retinol level and reduced activity of glutathione peroxidase. Contrary to popular opinion, newborns can be a COVID-19-susceptible age group and require more close monitoring of metabolic reactions during the period of neonatal adaptation that is an aggravating background during infection.

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