Cargando…
NLRP6 deficiency expands a novel CD103(+) B cell population that confers immune tolerance in NOD mice
INTRODUCTION: Gut microbiota have been linked to modulating susceptibility to Type 1 diabetes; however, there are many ways in which the microbiota interact with host cells, including through microbial ligand binding to intracellular inflammasomes (large multi-subunit proteins) to initiate immune re...
Autores principales: | Pearson, James A., Peng, Jian, Huang, Juan, Yu, Xiaoqing, Tai, Ningwen, Hu, Youjia, Sha, Sha, Flavell, Richard A., Zhao, Hongyu, Wong, F. Susan, Wen, Li |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995752/ https://www.ncbi.nlm.nih.gov/pubmed/36911699 http://dx.doi.org/10.3389/fimmu.2023.1147925 |
Ejemplares similares
-
Microbial antigen mimics activate diabetogenic CD8 T cells in NOD mice
por: Tai, Ningwen, et al.
Publicado: (2016) -
IL-10 Deficiency Accelerates Type 1 Diabetes Development via Modulation of Innate and Adaptive Immune Cells and Gut Microbiota in BDC2.5 NOD Mice
por: Huang, Juan, et al.
Publicado: (2021) -
Toll-like receptor 7 deficiency suppresses type 1 diabetes development by modulating B-cell differentiation and function
por: Huang, Juan, et al.
Publicado: (2021) -
Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens
por: Normand, Sylvain, et al.
Publicado: (2018) -
Genetic deficiency of NOD2 confers resistance to invasive aspergillosis
por: Gresnigt, Mark S., et al.
Publicado: (2018)