Histone deacetylase 8 inhibition prevents the progression of peritoneal fibrosis by counteracting the epithelial-mesenchymal transition and blockade of M2 macrophage polarization

BACKGROUND: Peritoneal dialysis (PD) is an effective replacement therapy for end-stage renal disease patients. However, long-term exposure to peritoneal dialysate will lead to the development of peritoneal fibrosis. Epigenetics has been shown to play an important role in peritoneal fibrosis, but the...

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Detalles Bibliográficos
Autores principales: Zhou, Xun, Chen, Hui, Shi, Yingfeng, Li, Jinqing, Ma, Xiaoyan, Du, Lin, Hu, Yan, Tao, Min, Zhong, Qin, Yan, Danying, Zhuang, Shougang, Liu, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995794/
https://www.ncbi.nlm.nih.gov/pubmed/36911746
http://dx.doi.org/10.3389/fimmu.2023.1137332

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