Cargando…
Lymphocyte activation gene (LAG)-3 is a potential immunotherapeutic target for microsatellite stable, programmed death-ligand 1 (PD-L1)-positive endometrioid endometrial cancer
OBJECTIVE: Immune checkpoint inhibitors have been widely used in the treatment of endometrial cancer (EC) with microsatellite instability-hypermutated (MSI-H). However, there is an unmet need for microsatellite stable (MSS) EC because of their modest activity. This study aimed to identify potential...
Autores principales: | Hong, Jin Hwa, Cho, Hyun Woong, Ouh, Yung-Taek, Lee, Jae Kwan, Chun, Yikyeong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology; Japan Society of Gynecologic Oncology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995863/ https://www.ncbi.nlm.nih.gov/pubmed/36509464 http://dx.doi.org/10.3802/jgo.2023.34.e18 |
Ejemplares similares
-
Genomic landscape of advanced endometrial cancer analyzed by targeted next-generation sequencing and the cancer genome atlas (TCGA) dataset
por: Hong, Jin Hwa, et al.
Publicado: (2022) -
Effects of hormone therapy on recurrence in endometrial cancer survivors: a nationwide study using the Korean Health Insurance Review and Assessment Service database
por: Cho, Hyun-Woong, et al.
Publicado: (2019) -
Programmed death-1 (PD-1) expression in cervical intraepithelial neoplasia and its relationship with recurrence after conization
por: Chang, Hyeyoon, et al.
Publicado: (2018) -
Microsatellite instability derived JAK1 frameshift mutations are associated with tumor immune evasion in endometrioid endometrial cancer
por: Stelloo, Ellen, et al.
Publicado: (2016) -
Identification of a Subset of Microsatellite-Stable Endometrial Carcinoma with High PD-L1 and CD8+ Lymphocytes
por: Crumley, Suzanne, et al.
Publicado: (2018)