Cargando…

Molecular profile-based recommendations for postoperative adjuvant therapy in early endometrial cancer with high-intermediate or intermediate risk: a Chinese randomized phase III trial (PROBEAT)

BACKGROUND: The use of molecular categorisation is shifting paradigm towards the use of molecular information to refine risk stratification in endometrial cancer (EC). To date, evidence to support molecular-guided therapies is limited to retrospective studies and secondary molecular analyses of pati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yang, Zhu, Changkun, Xie, Hongyu, Chen, Yaxia, Lv, Weiguo, Xie, Xing, Wang, Xinyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology; Japan Society of Gynecologic Oncology 2023
Materias:	Clinical Trial Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995864/ https://www.ncbi.nlm.nih.gov/pubmed/36659832 http://dx.doi.org/10.3802/jgo.2023.34.e37

Ejemplares similares

PORTEC-4a: international randomized trial of molecular profile-based adjuvant treatment for women with high-intermediate risk endometrial cancer
por: van den Heerik, Anne Sophie V M, et al.
Publicado: (2020)

Sentinel lymph Node mapping versus systematic pelvic lymphadenectomy on the prognosis for patients with intermediate-high-risk Endometrial Cancer confined to the uterus before surgery: trial protocol for a non-inferiority randomized controlled trial (SNEC trial)
por: Guan, Jun, et al.
Publicado: (2021)

One-week vaginal brachytherapy schedule as exclusive adjuvant post-operative treatment in intermediate- and high-intermediate-risk endometrial cancer patients
por: De Sanctis, Vitaliana, et al.
Publicado: (2020)

Ultra‐hypofractionated radiation therapy for unfavourable intermediate‐risk and high‐risk prostate cancer is safe and effective: 5‐year outcomes of a phase II trial
por: Macias, Victor A., et al.
Publicado: (2019)

A questionnaire to assess the health information literacy of patients with intermediate‐stage chronic kidney disease
por: Zhao, Fei, et al.
Publicado: (2023)

PARTNER 2A & SAPIEN 3: TAVI for intermediate risk patients
por: ElGuindy, Ahmed
Publicado: (2016)

Refining adjuvant treatment in endometrial cancer based on molecular features: the RAINBO clinical trial program
Publicado: (2023)

Impact of Prophylactic Ranibizumab to Prevent Neovascular Age-Related Macular Degeneration on Eyes With Intermediate Age-Related Macular Degeneration
por: Chan, Clement K., et al.
Publicado: (2023)

Adjuvant chemoradiotherapy versus chemotherapy or radiotherapy in advanced endometrial cancer: a systematic review and meta-analysis
por: Winarto, Hariyono, et al.
Publicado: (2022)

Safety and efficacy of frequency-domain optical coherence tomography in evaluating and treating intermediate coronary lesions
por: Khurwolah, Mohammad Reeaze, et al.
Publicado: (2018)

The “Sandwich” Schedule: A Well-Tolerated Adjuvant Treatment Both in Intermediate–High- and High-Risk Endometrial Cancer
por: Ferrero, Annamaria, et al.
Publicado: (2022)

Transperineal prostate brachytherapy, using I-125 seed with or without adjuvant androgen deprivation, in patients with intermediate-risk prostate cancer: study protocol for a phase III, multicenter, randomized, controlled trial
por: Miki, Kenta, et al.
Publicado: (2010)

A Trial Protocol to Investigate the Incidence of Postoperative Bowel Obstruction after Laparoscopic Colorectal Cancer Surgery Using an Absorbable Adhesion Barrier Material (INTERCEED(Ⓡ)) (Balsam CEED Study): A Prospective, Multicenter, Observational Study
por: Sonoda, Hiromichi, et al.
Publicado: (2021)

Open Surgery including Lymphadenectomy without Adjuvant Therapy for Uterine-Confined Intermediate- and High-Risk Endometrioid Endometrial Carcinoma
por: Otsuka, Isao, et al.
Publicado: (2022)

Impact of vaginal brachytherapy in intermediate and high-intermediate risk endometrial cancer: a multicenter study from the FRANCOGYN group
por: Reboux, Pierre-Alain, et al.
Publicado: (2019)

Laparoscopic surgery for low, intermediate and high-risk endometrial cancer
por: Vardar, Mehmet Ali, et al.
Publicado: (2018)

Postoperative adjuvant chemotherapy combined with intracavitary brachytherapy in early-stage cervical cancer patients with intermediate risk factors
por: Yu, Hao, et al.
Publicado: (2016)

Dissection of Mouse Hippocampus with Its Dorsal, Intermediate and Ventral Subdivisions Combined with Molecular Validation
por: Jaszczyk, Aneta, et al.
Publicado: (2022)

Phase 1 study of oral azacitidine (CC-486) plus R-CHOP in previously untreated intermediate- to high-risk DLBCL
por: Martin, Peter, et al.
Publicado: (2022)

Improving interMediAte Risk management. MARK study
por: Martí, Ruth, et al.
Publicado: (2011)

Should the Optimal Adjuvant Treatment for Patients With Early-Stage Endometrial Cancer With High-Intermediate Risk Factors Depend on Tumor Grade?
por: Lan, Chunyan, et al.
Publicado: (2015)

Ten-year results of the PORTEC-2 trial for high-intermediate risk endometrial carcinoma: improving patient selection for adjuvant therapy
por: Wortman, B. G., et al.
Publicado: (2018)

The BIG 2.04 MRC/EORTC SUPREMO Trial: pathology quality assurance of a large phase 3 randomised international clinical trial of postmastectomy radiotherapy in intermediate-risk breast cancer
por: Thomas, J. S., et al.
Publicado: (2017)

OncoVee™-MiniPDX-guided anticancer treatment for HER2-negative intermediate-advanced gastric cancer patients: a single-arm, open-label phase I clinical study
por: Zhang, Baonan, et al.
Publicado: (2023)

Integration of immunotherapy into adjuvant therapy for resected non-small-cell lung cancer: ALCHEMIST chemo-IO (ACCIO)
por: Sands, Jacob M, et al.
Publicado: (2021)

Assembly and Cryo-EM structure determination of yeast mitochondrial RNA polymerase initiation complex intermediates
por: Martinez, Sergio E., et al.
Publicado: (2021)

Prospective assessment of the decision-making impact of the Breast Cancer Index in recommending extended adjuvant endocrine therapy for patients with early-stage ER-positive breast cancer
por: Sanft, Tara, et al.
Publicado: (2015)

Analysing the administration of an intermediate level of outpatient palliative care in Germany and developing recommendations for improvement (Polite): A study protocol for a mixed-methods study
por: Stiel, Stephanie, et al.
Publicado: (2021)

Phase III study of long-term prognosis of estrogen receptor-positive early breast cancer treated with neoadjuvant endocrine therapy with/without adjuvant chemotherapy
por: Iwata, Hiroji, et al.
Publicado: (2023)

A Phase I Dose‐Escalation Study of Clofarabine in Patients with Relapsed or Refractory Low‐Grade or Intermediate‐Grade B‐Cell or T‐Cell Lymphoma
por: Foss, Francine Marie, et al.
Publicado: (2018)

Randomised trial of proton vs. carbon ion radiation therapy in patients with low and intermediate grade chondrosarcoma of the skull base, clinical phase III study
por: Nikoghosyan, Anna V, et al.
Publicado: (2010)

Adjuvant Treatment of Intermediate Risk Non-muscle Invasive Bladder Cancer
por: DRĂGOESCU, O., et al.
Publicado: (2014)

Adjuvant Radioiodine for Intermediate-Risk Papillary Thyroid Cancer—To Treat or Not to Treat
por: van Velsen, Evert F S, et al.
Publicado: (2023)

Remote Therapy to Improve Outcomes in Lung Transplant Recipients: Design of the INSPIRE-III Randomized Clinical Trial
por: Blumenthal, James A., et al.
Publicado: (2020)

KEYNOTE-859: a Phase III study of pembrolizumab plus chemotherapy in gastric/gastroesophageal junction adenocarcinoma
por: Tabernero, Josep, et al.
Publicado: (2021)

Identification and Spectroscopic Characterization of Nonheme Iron(III) Hypochlorite Intermediates**
por: Draksharapu, Apparao, et al.
Publicado: (2015)

Identification and Spectroscopic Characterization of Nonheme Iron(III) Hypochlorite Intermediates
por: Draksharapu, Apparao, et al.
Publicado: (2015)

Type III intermediate filaments as targets and effectors of electrophiles and oxidants
por: Viedma-Poyatos, Álvaro, et al.
Publicado: (2020)

Role of lymphadenectomy in intermediate-risk endometrial cancer: a matched-pair study
por: Coronado, Pluvio J., et al.
Publicado: (2018)

Ceftobiprole versus daptomycin in Staphylococcus aureus bacteremia: a novel protocol for a double-blind, Phase III trial
por: Hamed, Kamal, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ceofgqkbtpoalgaessqr30eqai