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SARS-CoV-2 antibodies in dogs and cats in a highly infected area of Brazil during the pandemic

SARS-CoV-2 was a worldwide threat during the COVID-19 pandemic, and the state of Mato Grosso had the second highest mortality rate in Brazil, with 427. 4 deaths/100,000 inhabitants. However, no large-scale study among dogs and cats in such highly infected areas of Brazil has so far been conducted. A...

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Autores principales: Jarrah, Samar Afif, Kmetiuk, Louise Bach, Valleriani, Fabrizia, Bonfini, Barbara, Lorusso, Alessio, Vasinioti, Violetta, Decaro, Nicola, dos Santos, Marco Tulio, Spohr, Kledir Anderson Hofstaetter, Pratelli, Annamaria, Serroni, Anna, Capista, Sara, Sousa, Valéria Regia Franco, Biondo, Alexander Welker, Nakazato, Luciano, Dutra, Valéria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995883/
https://www.ncbi.nlm.nih.gov/pubmed/36908526
http://dx.doi.org/10.3389/fvets.2023.1111728
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author Jarrah, Samar Afif
Kmetiuk, Louise Bach
Valleriani, Fabrizia
Bonfini, Barbara
Lorusso, Alessio
Vasinioti, Violetta
Decaro, Nicola
dos Santos, Marco Tulio
Spohr, Kledir Anderson Hofstaetter
Pratelli, Annamaria
Serroni, Anna
Capista, Sara
Sousa, Valéria Regia Franco
Biondo, Alexander Welker
Nakazato, Luciano
Dutra, Valéria
author_facet Jarrah, Samar Afif
Kmetiuk, Louise Bach
Valleriani, Fabrizia
Bonfini, Barbara
Lorusso, Alessio
Vasinioti, Violetta
Decaro, Nicola
dos Santos, Marco Tulio
Spohr, Kledir Anderson Hofstaetter
Pratelli, Annamaria
Serroni, Anna
Capista, Sara
Sousa, Valéria Regia Franco
Biondo, Alexander Welker
Nakazato, Luciano
Dutra, Valéria
author_sort Jarrah, Samar Afif
collection PubMed
description SARS-CoV-2 was a worldwide threat during the COVID-19 pandemic, and the state of Mato Grosso had the second highest mortality rate in Brazil, with 427. 4 deaths/100,000 inhabitants. However, no large-scale study among dogs and cats in such highly infected areas of Brazil has so far been conducted. Accordingly, the present study reports on a serosurvey among dogs and cats in Cuiabá, capital of Mato Grosso from November 2020 to July 2021, where the human mortality rate was 605/100,000 at that time. Overall, 33/762 dogs (4.3%) and 4/182 cats (2.2%) were found to be seropositive for SARS-CoV-2 through ELISA, and 3/762 dogs (0.4%) and 3/182 cats (1.6%) were seropositive through the serum neutralization test. Cats presented higher seroprevalence with higher titers of neutralizing antibodies. Although N-protein based ELISA may be a good screening test, cross-reactivity with other canine coronaviruses may impair its diagnostic use among dogs.
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spelling pubmed-99958832023-03-10 SARS-CoV-2 antibodies in dogs and cats in a highly infected area of Brazil during the pandemic Jarrah, Samar Afif Kmetiuk, Louise Bach Valleriani, Fabrizia Bonfini, Barbara Lorusso, Alessio Vasinioti, Violetta Decaro, Nicola dos Santos, Marco Tulio Spohr, Kledir Anderson Hofstaetter Pratelli, Annamaria Serroni, Anna Capista, Sara Sousa, Valéria Regia Franco Biondo, Alexander Welker Nakazato, Luciano Dutra, Valéria Front Vet Sci Veterinary Science SARS-CoV-2 was a worldwide threat during the COVID-19 pandemic, and the state of Mato Grosso had the second highest mortality rate in Brazil, with 427. 4 deaths/100,000 inhabitants. However, no large-scale study among dogs and cats in such highly infected areas of Brazil has so far been conducted. Accordingly, the present study reports on a serosurvey among dogs and cats in Cuiabá, capital of Mato Grosso from November 2020 to July 2021, where the human mortality rate was 605/100,000 at that time. Overall, 33/762 dogs (4.3%) and 4/182 cats (2.2%) were found to be seropositive for SARS-CoV-2 through ELISA, and 3/762 dogs (0.4%) and 3/182 cats (1.6%) were seropositive through the serum neutralization test. Cats presented higher seroprevalence with higher titers of neutralizing antibodies. Although N-protein based ELISA may be a good screening test, cross-reactivity with other canine coronaviruses may impair its diagnostic use among dogs. Frontiers Media S.A. 2023-02-23 /pmc/articles/PMC9995883/ /pubmed/36908526 http://dx.doi.org/10.3389/fvets.2023.1111728 Text en Copyright © 2023 Jarrah, Kmetiuk, Valleriani, Bonfini, Lorusso, Vasinioti, Decaro, dos Santos, Spohr, Pratelli, Serroni, Capista, Sousa, Biondo, Nakazato and Dutra. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Jarrah, Samar Afif
Kmetiuk, Louise Bach
Valleriani, Fabrizia
Bonfini, Barbara
Lorusso, Alessio
Vasinioti, Violetta
Decaro, Nicola
dos Santos, Marco Tulio
Spohr, Kledir Anderson Hofstaetter
Pratelli, Annamaria
Serroni, Anna
Capista, Sara
Sousa, Valéria Regia Franco
Biondo, Alexander Welker
Nakazato, Luciano
Dutra, Valéria
SARS-CoV-2 antibodies in dogs and cats in a highly infected area of Brazil during the pandemic
title SARS-CoV-2 antibodies in dogs and cats in a highly infected area of Brazil during the pandemic
title_full SARS-CoV-2 antibodies in dogs and cats in a highly infected area of Brazil during the pandemic
title_fullStr SARS-CoV-2 antibodies in dogs and cats in a highly infected area of Brazil during the pandemic
title_full_unstemmed SARS-CoV-2 antibodies in dogs and cats in a highly infected area of Brazil during the pandemic
title_short SARS-CoV-2 antibodies in dogs and cats in a highly infected area of Brazil during the pandemic
title_sort sars-cov-2 antibodies in dogs and cats in a highly infected area of brazil during the pandemic
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995883/
https://www.ncbi.nlm.nih.gov/pubmed/36908526
http://dx.doi.org/10.3389/fvets.2023.1111728
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