GSTP1-mediated S-glutathionylation of Pik3r1 is a redox hub that inhibits osteoclastogenesis through regulating autophagic flux

Glutathione S-transferase P1(GSTP1) is known for its transferase and detoxification activity. Based on disease-phenotype genetic associations, we found that GSTP1 might be associated with bone mineral density through Mendelian randomization analysis. Therefore, this study was performed both in vitro...

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Detalles Bibliográficos
Autores principales: Ji, Xiaoxiao, Hong, Jianqiao, Yang, Weinan, Yao, Minjun, Wang, Jie, Jiang, Guangyao, Wang, Yibo, Li, Congsun, Lin, Jiyan, Mou, Haochen, Li, Chaozhong, Li, Sihao, Chen, Yazhou, Shi, Minming, Wang, Wei, Lu, Fei, Wu, Haobo, Zhao, Xiang, Qi, Yiying, Yan, Shigui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995948/
https://www.ncbi.nlm.nih.gov/pubmed/36870110
http://dx.doi.org/10.1016/j.redox.2023.102635

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