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Successful management of a rare radius schwannoma mimicking malignant bone tumors: A case report and literature review

BACKGROUND: Schwannomas are benign tumors originating from Schwann cells, frequently occurring in the spinal cord and peripheral nerves. Intraosseous schwannomas, a rare subset, account for approximately 0.2% of schwannomas. Intraosseous schwannomas commonly impinge the mandible, followed by the sac...

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Autores principales: Sun, Nianzhe, Khan, Umar Zeb, Zeng, Lei, Wu, Panfeng, Xiong, Qin, Peng, Lushan, Yu, Hong, Tang, Juyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996063/
https://www.ncbi.nlm.nih.gov/pubmed/36911622
http://dx.doi.org/10.3389/fsurg.2023.1108942
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author Sun, Nianzhe
Khan, Umar Zeb
Zeng, Lei
Wu, Panfeng
Xiong, Qin
Peng, Lushan
Yu, Hong
Tang, Juyu
author_facet Sun, Nianzhe
Khan, Umar Zeb
Zeng, Lei
Wu, Panfeng
Xiong, Qin
Peng, Lushan
Yu, Hong
Tang, Juyu
author_sort Sun, Nianzhe
collection PubMed
description BACKGROUND: Schwannomas are benign tumors originating from Schwann cells, frequently occurring in the spinal cord and peripheral nerves. Intraosseous schwannomas, a rare subset, account for approximately 0.2% of schwannomas. Intraosseous schwannomas commonly impinge the mandible, followed by the sacrum and the spine. By far, only three cases of radius intraosseous schwannomas have been reported in PubMed. The tumor was treated differently in all three cases, resulting in different outcomes. CASE PRESENTATION: A 29-year-old male construction engineer who complained of a painless mass on the radial aspect of the right forearm was diagnosed with an intraosseous schwannoma of the radius based on radiography, three-dimensional computed tomography reconstruction, magnetic resonance imaging, pathological examination, and immunohistochemistry. A different surgical approach was employed to reconstruct the radial graft defect using bone microrepair techniques, resulting in more reliable bone healing and early functional recovery. Meanwhile, no clinical and radiographic findings suggestive of recurrence were observed at the 12-month follow-up. CONCLUSION: Vascularized bone flap transplantation combined with three-dimensional imaging reconstruction planning might yield better results for repairing small segmental bone defects of the radius caused by intraosseous schwannomas.
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spelling pubmed-99960632023-03-10 Successful management of a rare radius schwannoma mimicking malignant bone tumors: A case report and literature review Sun, Nianzhe Khan, Umar Zeb Zeng, Lei Wu, Panfeng Xiong, Qin Peng, Lushan Yu, Hong Tang, Juyu Front Surg Surgery BACKGROUND: Schwannomas are benign tumors originating from Schwann cells, frequently occurring in the spinal cord and peripheral nerves. Intraosseous schwannomas, a rare subset, account for approximately 0.2% of schwannomas. Intraosseous schwannomas commonly impinge the mandible, followed by the sacrum and the spine. By far, only three cases of radius intraosseous schwannomas have been reported in PubMed. The tumor was treated differently in all three cases, resulting in different outcomes. CASE PRESENTATION: A 29-year-old male construction engineer who complained of a painless mass on the radial aspect of the right forearm was diagnosed with an intraosseous schwannoma of the radius based on radiography, three-dimensional computed tomography reconstruction, magnetic resonance imaging, pathological examination, and immunohistochemistry. A different surgical approach was employed to reconstruct the radial graft defect using bone microrepair techniques, resulting in more reliable bone healing and early functional recovery. Meanwhile, no clinical and radiographic findings suggestive of recurrence were observed at the 12-month follow-up. CONCLUSION: Vascularized bone flap transplantation combined with three-dimensional imaging reconstruction planning might yield better results for repairing small segmental bone defects of the radius caused by intraosseous schwannomas. Frontiers Media S.A. 2023-02-23 /pmc/articles/PMC9996063/ /pubmed/36911622 http://dx.doi.org/10.3389/fsurg.2023.1108942 Text en © 2023 Sun, Khan, Zeng, Wu, Xiong, Peng, Yu and Tang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Sun, Nianzhe
Khan, Umar Zeb
Zeng, Lei
Wu, Panfeng
Xiong, Qin
Peng, Lushan
Yu, Hong
Tang, Juyu
Successful management of a rare radius schwannoma mimicking malignant bone tumors: A case report and literature review
title Successful management of a rare radius schwannoma mimicking malignant bone tumors: A case report and literature review
title_full Successful management of a rare radius schwannoma mimicking malignant bone tumors: A case report and literature review
title_fullStr Successful management of a rare radius schwannoma mimicking malignant bone tumors: A case report and literature review
title_full_unstemmed Successful management of a rare radius schwannoma mimicking malignant bone tumors: A case report and literature review
title_short Successful management of a rare radius schwannoma mimicking malignant bone tumors: A case report and literature review
title_sort successful management of a rare radius schwannoma mimicking malignant bone tumors: a case report and literature review
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996063/
https://www.ncbi.nlm.nih.gov/pubmed/36911622
http://dx.doi.org/10.3389/fsurg.2023.1108942
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