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Influence of glycoprotein MUC1 on trafficking of the Ca(2+)-selective ion channels, TRPV5 and TRPV6, and on in vivo calcium homeostasis

Polymorphism of the gene encoding mucin 1 (MUC1) is associated with skeletal and dental phenotypes in human genomic studies. Animals lacking MUC1 exhibit mild reduction in bone density. These phenotypes could be a consequence of modulation of bodily Ca homeostasis by MUC1, as suggested by the previo...

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Detalles Bibliográficos
Autores principales: Al-bataineh, Mohammad M., Kinlough, Carol L., Marciszyn, Allison, Lam, Tracey, Ye, Lorena, Kidd, Kendrah, Maggiore, Joseph C., Poland, Paul A., Kmoch, Stanislav, Bleyer, Anthony, Bain, Daniel J., Montalbetti, Nicolas, Kleyman, Thomas R., Hughey, Rebecca P., Ray, Evan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996365/
https://www.ncbi.nlm.nih.gov/pubmed/36682497
http://dx.doi.org/10.1016/j.jbc.2023.102925