Cargando…
Tracking the progeny of adoptively transferred virus-specific T cells in patients posttransplant using TCR sequencing
Adoptive cellular therapies with T cells are increasingly used to treat a variety of conditions. For instance, in a recent phase 1/2 trial, we prophylactically administered multivirus-specific T-cell products to protect recipients of T-cell–depleted allogeneic stem cell grafts against viral reactiva...
Autores principales: | Huisman, W., Roex, M. C. J., Hageman, L., Koster, E. A. S., Veld, S. A. J., Hoogstraten, C., van Balen, P., van Egmond, H. M., van Bergen, C. A. M., Einsele, H., Germeroth, L., Amsen, D., Falkenburg, J. H. F., Jedema, I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996373/ https://www.ncbi.nlm.nih.gov/pubmed/36121440 http://dx.doi.org/10.1182/bloodadvances.2022007270 |
Ejemplares similares
-
Amino acids at position 5 in the peptide/MHC binding region of a public virus‐specific TCR are completely inter‐changeable without loss of function
por: Huisman, Wesley, et al.
Publicado: (2022) -
Public T-Cell Receptors (TCRs) Revisited by Analysis of the Magnitude of Identical and Highly-Similar TCRs in Virus-Specific T-Cell Repertoires of Healthy Individuals
por: Huisman, Wesley, et al.
Publicado: (2022) -
Magnitude of Off-Target Allo-HLA Reactivity by Third-Party Donor-Derived Virus-Specific T Cells Is Dictated by HLA-Restriction
por: Huisman, Wesley, et al.
Publicado: (2021) -
The allogeneic HLA-DP-restricted T-cell repertoire provoked by allogeneic dendritic cells contains T cells that show restricted recognition of hematopoietic cells including primary malignant cells
por: Laghmouchi, Aicha, et al.
Publicado: (2019) -
Identification of Functional HLA-A*01:01–Restricted Epstein-Barr Latent Membrane Protein 2–Specific T-Cell Receptors( )
por: Huisman, Wesley, et al.
Publicado: (2020)