Reiter’s syndrome following intravesical Bacillus Calmette-Guerin therapy for bladder carcinoma: Case report

Reiter syndrome is an autoimmune condition that develops in as a reactive response to GI or GU related infectious and rarely related to Intravesical BCG. it is a triad of conjunctivitis, urethritis, and arthritis. Here we report the case of a female patient who developed acute Reiter’s syndrome following intravesical Bacillus Calmette–Guerin (BCG) immunotherapy for superficial bladder cancer. After the sixth dose in the maintenance phase of treatment the patient developed conjunctivitis, aseptic urethritis, and polyarthritis consistent with a diagnosis of Reiter’s syndrome. In this patient non-steroidal anti-inflammatory drugs (NSAIDs), oral steroids and anti-tuberculosis drugs were administered with complete resolution of symptoms.