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Andrographolide suppresses aerobic glycolysis and induces apoptotic cell death by inhibiting pyruvate dehydrogenase kinase 1 expression
Metabolic disorder is a major characteristic of cancer cells, and controlling genes involved in metabolic shifts can be an effective strategy for cancer treatment. Andrographolide (AG), a diterpenoid lactone, is widely recognized as a natural anticancer drug due to its ability to inhibit cancer grow...
Autores principales: | Yang, Eun-Sun, Do, Yunju, Cheon, Se-Yun, Kim, Bosung, Ling, Jin, Cho, Min Kyoung, Kim, Taekyung, Bae, Sung-Jin, Ha, Ki-Tae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996679/ https://www.ncbi.nlm.nih.gov/pubmed/36825595 http://dx.doi.org/10.3892/or.2023.8509 |
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