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Conformational Control of Fast Asparagine Deamidation in a Norovirus Capsid Protein
[Image: see text] Accelerated spontaneous deamidation of asparagine 373 and subsequent conversion into an isoaspartate has been shown to attenuate the binding of histo blood group antigens (HBGAs) to the protruding domain (P-domain) of the capsid protein of a prevalent norovirus strain (GII.4). Here...
Autores principales: | Creutznacher, Robert, Schulze-Niemand, Eric, König, Patrick, Stanojlovic, Vesna, Mallagaray, Alvaro, Peters, Thomas, Stein, Matthias, Schubert, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996831/ https://www.ncbi.nlm.nih.gov/pubmed/36808948 http://dx.doi.org/10.1021/acs.biochem.2c00656 |
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