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Exonized Alu repeats in the 3’UTR of a CYP20A1_Alu-LT transcript act as a miRNA sponge

OBJECTIVE: Alu repeats have gained huge importance in the creation and modification of regulatory networks. We previously reported a unique isoform of human CYP20A1 i.e. CYP20A1_Alu-LT with 23 Alu repeats exonized in its 9 kb long 3’UTR with 4742 potential binding sites for 994 miRNAs. The role of t...

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Detalles Bibliográficos
Autores principales: Singhal, Khushboo, Dhamija, Sonam, Mukerji, Mitali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996890/
https://www.ncbi.nlm.nih.gov/pubmed/36895043
http://dx.doi.org/10.1186/s13104-023-06289-z