Helicobacter pylori outer membrane vesicles induce astrocyte reactivity through nuclear factor-κappa B activation and cause neuronal damage in vivo in a murine model

BACKGROUND: Helicobacter pylori (Hp) infects the stomach of 50% of the world’s population. Importantly, chronic infection by this bacterium correlates with the appearance of several extra-gastric pathologies, including neurodegenerative diseases. In such conditions, brain astrocytes become reactive...

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Detalles Bibliográficos
Autores principales: Palacios, Esteban, Lobos-González, Lorena, Guerrero, Simón, Kogan, Marcelo J., Shao, Baohai, Heinecke, Jay W., Quest, Andrew F. G., Leyton, Lisette, Valenzuela-Valderrama, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996972/
https://www.ncbi.nlm.nih.gov/pubmed/36895046
http://dx.doi.org/10.1186/s12974-023-02728-7

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