Loss of TTC17 promotes breast cancer metastasis through RAP1/CDC42 signaling and sensitizes it to rapamycin and paclitaxel

BACKGROUND: Breast cancer (BC) metastasis is the leading cause of poor prognosis and therapeutic failure. However, the mechanisms underlying cancer metastasis are far from clear. METHODS: We screened candidate genes related to metastasis through genome-wide CRISPR screening and high-throughput seque...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jingyao, Guo, Fengzhu, Li, Chunxiao, Wang, Yang, Wang, Jinsong, Sun, Fangzhou, Zhou, Yantong, Ma, Fei, Zhang, Bailin, Qian, Haili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996991/
https://www.ncbi.nlm.nih.gov/pubmed/36895029
http://dx.doi.org/10.1186/s13578-023-01004-8

Ejemplares similares

Ejemplares similares