IL-22 alters gut microbiota composition and function to increase aryl hydrocarbon receptor activity in mice and humans

BACKGROUND: IL-22 is induced by aryl hydrocarbon receptor (AhR) signaling and plays a critical role in gastrointestinal barrier function through effects on antimicrobial protein production, mucus secretion, and epithelial cell differentiation and proliferation, giving it the potential to modulate th...

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Detalles Bibliográficos
Autores principales: Mar, Jordan S., Ota, Naruhisa, Pokorzynski, Nick D., Peng, Yutian, Jaochico, Allan, Sangaraju, Dewakar, Skippington, Elizabeth, Lekkerkerker, Annemarie N., Rothenberg, Michael E., Tan, Man-Wah, Yi, Tangsheng, Keir, Mary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997005/
https://www.ncbi.nlm.nih.gov/pubmed/36894983
http://dx.doi.org/10.1186/s40168-023-01486-1

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