Impact of Gastric pH Variations on the Release of Amorphous Solid Dispersion Formulations Containing a Weakly Basic Drug and Enteric Polymers

[Image: see text] Enteric polymers are widely used in amorphous solid dispersion (ASD) formulations. The aim of the current study was to explore ASD failure mechanisms across a wide range of pH conditions that mimic in vivo gastric compartment variations where enteric polymers such as hydroxypropyl...

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Detalles Bibliográficos
Autores principales: Nguyen, Hanh Thuy, Van Duong, Tu, Taylor, Lynne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997068/
https://www.ncbi.nlm.nih.gov/pubmed/36730186
http://dx.doi.org/10.1021/acs.molpharmaceut.2c00895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997068/
https://www.ncbi.nlm.nih.gov/pubmed/36730186
http://dx.doi.org/10.1021/acs.molpharmaceut.2c00895

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