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Protective effects of omega-3 fatty acids in a blood–brain barrier-on-chip model and on postoperative delirium-like behaviour in mice
BACKGROUND: Peripheral surgical trauma can trigger neuroinflammation and ensuing neurological complications, such as delirium. The mechanisms whereby surgery contributes to postoperative neuroinflammation remain unclear and without effective therapies. Here, we developed a microfluidic-assisted bloo...
Autores principales: | Yang, Ting, Velagapudi, Ravikanth, Kong, Cuicui, Ko, Unghyeon, Kumar, Vardhman, Brown, Paris, Franklin, Nathan O., Zhang, Xiaobei, Caceres, Ana I., Min, Hyunjung, Filiano, Anthony J., Rodriguiz, Ramona M., Wetsel, William C., Varghese, Shyni, Terrando, Niccolò |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997088/ https://www.ncbi.nlm.nih.gov/pubmed/35778276 http://dx.doi.org/10.1016/j.bja.2022.05.025 |
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